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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIAS1
All Species:
15.45
Human Site:
S586
Identified Species:
34
UniProt:
O75925
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75925
NP_057250.1
651
71836
S586
R
F
F
P
Y
T
S
S
Q
M
F
L
D
Q
L
Chimpanzee
Pan troglodytes
XP_523109
766
83908
S701
R
F
F
P
Y
T
S
S
Q
M
F
L
D
Q
L
Rhesus Macaque
Macaca mulatta
XP_001082800
642
70843
Q578
F
F
P
Y
T
S
S
Q
M
F
L
D
Q
L
S
Dog
Lupus familis
XP_535524
651
71773
S586
R
F
F
P
Y
T
S
S
Q
M
F
L
D
Q
L
Cat
Felis silvestris
Mouse
Mus musculus
O88907
651
71599
S586
R
F
F
P
Y
T
S
S
Q
M
F
L
D
Q
L
Rat
Rattus norvegicus
O70260
628
68345
G564
G
H
F
F
Q
F
R
G
T
P
P
H
F
L
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516107
756
82793
F685
L
L
H
S
S
R
F
F
P
Y
A
S
S
Q
M
Chicken
Gallus gallus
NP_001026627
564
62782
Q500
G
I
L
N
L
P
H
Q
A
S
P
V
S
R
T
Frog
Xenopus laevis
NP_001079161
649
71676
S585
S
R
F
F
P
Y
T
S
S
Q
L
F
L
D
Q
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q94361
793
89556
S679
G
E
Q
S
A
N
S
S
T
Q
S
S
P
L
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q680Q4
884
97015
I614
D
D
E
N
D
L
V
I
T
P
G
P
A
Y
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.9
98.6
99.6
N.A.
98
58.6
N.A.
82.2
82.9
87
N.A.
N.A.
N.A.
N.A.
24
N.A.
Protein Similarity:
100
84.9
98.6
99.8
N.A.
98.7
72
N.A.
84.2
85
94.3
N.A.
N.A.
N.A.
N.A.
40.9
N.A.
P-Site Identity:
100
100
13.3
100
N.A.
100
6.6
N.A.
6.6
0
13.3
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
100
100
20
100
N.A.
100
6.6
N.A.
13.3
13.3
20
N.A.
N.A.
N.A.
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
0
0
10
0
10
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
10
0
0
10
0
0
0
0
0
0
10
37
10
0
% D
% Glu:
0
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
10
46
55
19
0
10
10
10
0
10
37
10
10
0
0
% F
% Gly:
28
0
0
0
0
0
0
10
0
0
10
0
0
0
10
% G
% His:
0
10
10
0
0
0
10
0
0
0
0
10
0
0
0
% H
% Ile:
0
10
0
0
0
0
0
10
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
10
10
10
0
10
10
0
0
0
0
19
37
10
28
37
% L
% Met:
0
0
0
0
0
0
0
0
10
37
0
0
0
0
10
% M
% Asn:
0
0
0
19
0
10
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
10
37
10
10
0
0
10
19
19
10
10
0
0
% P
% Gln:
0
0
10
0
10
0
0
19
37
19
0
0
10
46
10
% Q
% Arg:
37
10
0
0
0
10
10
0
0
0
0
0
0
10
0
% R
% Ser:
10
0
0
19
10
10
55
55
10
10
10
19
19
0
19
% S
% Thr:
0
0
0
0
10
37
10
0
28
0
0
0
0
0
10
% T
% Val:
0
0
0
0
0
0
10
0
0
0
0
10
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
37
10
0
0
0
10
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _